Special CIMED “EXCITE” SEMINAR

Please join us: Monday, February 27, 2017 at 12:00 PM

Special EXCITE Seminar

Structure and Mechanism of Endolysosomal Ion Channels”

Alexander Kintzer, Ph.D. 

Postdoctoral Fellow, Department of Biochemistry and Biophysics
University of California, San Francisco

Stahl Library, 426 McDonnell Sciences Building
Coffee & Cookies will be served

PROFILE:
Alex carried out his Ph.D. in Chemistry at UC Berkeley in 2012 with Bryan Krantz, discovering a novel octameric form of anthrax toxin, and describing the interaction of anthrax toxin and the poly-γ-d-glutamic acid capsule that leads to anthrax toxin translocation into the host (PNAS, 2012). He then moved on to post-Doctoral work with Bob Stroud at UCSF, examining endolysosomal ion channels using X-ray crystallography and cryoEM approaches. He recently determined the structure of a plant voltage-activated two-pore channel TPC1 (Nature, 2016) and is now resolving multiple states of TPC1 during activation by Ca2+ and voltage.

: http://cimed.wustl.edu/uncategorized/special-cimed-excite-seminar-2/kintzer-flyer/

Kintzer flyer