Robertson, Janice

Assistant Professor of Biochemistry and Molecular Biophysics

The goal of my research is to understand the how membrane proteins self-assemble and adopt their folded
structures to carry out specific biological functions in cell membranes.

Membrane proteins are the molecular gatekeepers of the cell, governing the passage of charged species and
thereby enabling the storage of potential energy that fuels biology. Despite their overwhelming importance, we
still do not understand many of the basic physical reactions of membrane proteins in the context of their native
solvent that is the cell membrane. The goal of my laboratory’s research is to provide a quantitative
understanding of the reactions of membrane proteins in lipid bilayers through an integration of membrane
protein biochemistry, single-molecule fluorescence microscopy and computational modeling. By combining
these disciplines, we are developing new approaches to investigate three long-standing questions in this field: